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Recognising Early Clinical Deterioration: What are we missing?

  • Jan 30
  • 2 min read

Updated: Feb 11


Evidence-based learning with guided reflection for CPD and revalidation 

Estimated Learning Time: 20 – 30 minutes 

Suitable for: Nurses, AHPs, clinical staff involved in direct patient care  

CPD Evidence: Yes – reflection template mapped to NMC and HCPC standards provided  

To explore this topic in greater depth, including practical case examples and structured assessment, view our related courses. 

 

Introduction 

Failure to recognise early clinical deterioration remains a significant contributor to avoidable patient harm. Subtle changes in physiology are often present hours before serious adverse events — yet these signs can be missed, misinterpreted, or normalised in busy clinical environments. 

 

Early recognition of deterioration is not about identifying the critically unwell patient — it is about recognising when something is starting to change and acting early. 

 

What Do We Mean by “Early Deterioration”? 

Clinical deterioration often begins with small but meaningful changes, including: 

  • Increasing respiratory rate 

  • Subtle drops in oxygen saturation 

  • Rising heart rate 

  • Changes in blood pressure trends 

  • Altered conscious level or behaviour 

  • Reduced urine output 

 

These changes may not trigger immediate concern in isolation but are significant when viewed together or over time. 

 

Common Reasons Deterioration Is Missed 

Research and incident reviews consistently highlight several recurring factors: 

  • Over-reliance on single observations rather than trends 

  • Incomplete or infrequent observations 

  • Normalisation of abnormal vital signs 

  • Lack of confidence in escalation 

  • Cognitive overload and time pressure 

 

Importantly, many of these are system and education issues, not individual failings. 

 

The Role of Respiratory Rate 

Many recent large-scale studies report that respiratory rate is one of the most sensitive early indicators of deterioration — yet it is also the most inaccurately measured. 

An unexplained increase in respiratory rate should always prompt further assessment, even if other observations appear within normal limits. 

 

Key point: 

A “normal” oxygen saturation does not rule out respiratory compromise. 

 

Escalation Is a Clinical Skill 

Recognising deterioration is only part of the process. Effective escalation requires: 

 

  • Confidence in clinical judgement 

  • Clear communication 

  • Understanding local escalation pathways 

  • Willingness to challenge reassurance bias 

 

Education that links physiology to decision-making improves both recognition and escalation. 

 

Implications and Reflection for Practice 

After engaging with this topic, consider: 

 

  • Are trends reviewed as well as single values in your area? 

  • How confident do you feel in escalating early concerns? 

  • Are early warning scores supporting or replacing clinical judgement? 

  • Can you think of a case you have been involved in where early deterioration was not identified? What would you do differently next time?  

 

Early recognition saves lives — but only when combined with timely action. 

 

Key References 

Aglen, S. et al. (2025) Respiratory Rate as a Predictor of Clinical Deterioration and Mortality: A Scoping Review. https://doi.org/10.1111/aas.70113Digital Object Identifier (DOI) 

Brekke IJ, Puntervoll LH, Pedersen PB, Kellett J, Brabrand M (2019) The value of vital sign trends in predicting and monitoring clinical deterioration: A systematic review. PLoS ONE 14(1): e0210875. https://doi.org/10.1371/journal.pone.0210875 

Royal College of Physicians. National Early Warning Score (NEWS2): Standardising the assessment of acute-illness severity in the NHS. 



Download our ready to use CPD Reflections template below.



 
 
 

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